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Compile Data Set for Download or QSAR

Marvin 2D Structure

Wt: 130.2
BDBM50149890Purchase

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kJ/mol)

Found 17 hits in this display   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-bungarotoxin


(Bungarus multicinctus)		BDBM50149890
PNG
(CHEMBL9324 | tetraethylammonium)
Show SMILES CC[N+](CC)(CC)CC
Show InChI InChI=1S/C8H20N/c1-5-9(6-2,7-3)8-4/h5-8H2,1-4H3/q+1
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>1.00E+4n/an/an/an/an/an/an/an/a



McGill University

Curated by PDSP Ki Database




J Neurochem 67: 145-54 (1996)


Article DOI: 10.1046/j.1471-4159.1996.67010145.x
BindingDB Entry DOI: 10.7270/Q2SX6BQW
More data for this
Ligand-Target Pair
Solute carrier family 22 member 1


(RAT)		BDBM50149890
PNG
(CHEMBL9324 | tetraethylammonium)
Show SMILES CC[N+](CC)(CC)CC
Show InChI InChI=1S/C8H20N/c1-5-9(6-2,7-3)8-4/h5-8H2,1-4H3/q+1
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 4.66E+4n/an/an/an/an/an/an/an/a



Kyoto University Hospital

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of TEA uptake (basolateral to cell) in OCT1-expressing MDCK cells

J Pharmacol Exp Ther 287: 800-5 (1998)


BindingDB Entry DOI: 10.7270/Q2D79CQ4
More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(RAT)		BDBM50149890
PNG
(CHEMBL9324 | tetraethylammonium)
Show SMILES CC[N+](CC)(CC)CC
Show InChI InChI=1S/C8H20N/c1-5-9(6-2,7-3)8-4/h5-8H2,1-4H3/q+1
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 5.22E+4n/an/an/an/an/an/an/an/a



Kyoto University Hospital

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of TEA uptake (apical to cell) in OCT2-expressing MDCK cells

J Pharmacol Exp Ther 287: 800-5 (1998)


BindingDB Entry DOI: 10.7270/Q2D79CQ4
More data for this
Ligand-Target Pair
Solute carrier family 22 member 1


(RAT)		BDBM50149890
PNG
(CHEMBL9324 | tetraethylammonium)
Show SMILES CC[N+](CC)(CC)CC
Show InChI InChI=1S/C8H20N/c1-5-9(6-2,7-3)8-4/h5-8H2,1-4H3/q+1
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 1.00E+5n/an/an/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of MPP+ uptake in Xenopus laevis oocytes

J Pharmacol Exp Ther 292: 1146-52 (2000)


BindingDB Entry DOI: 10.7270/Q2XS5WPJ
More data for this
Ligand-Target Pair
Solute carrier family 22 member 1


(Mus musculus)		BDBM50149890
PNG
(CHEMBL9324 | tetraethylammonium)
Show SMILES CC[N+](CC)(CC)CC
Show InChI InChI=1S/C8H20N/c1-5-9(6-2,7-3)8-4/h5-8H2,1-4H3/q+1
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 1.28E+5n/an/an/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of MPP+ uptake in Xenopus laevis oocytes

J Pharmacol Exp Ther 292: 1146-52 (2000)


BindingDB Entry DOI: 10.7270/Q2XS5WPJ
More data for this
Ligand-Target Pair
Solute carrier family 22 member 1


(Homo sapiens (Human))		BDBM50149890
PNG
(CHEMBL9324 | tetraethylammonium)
Show SMILES CC[N+](CC)(CC)CC
Show InChI InChI=1S/C8H20N/c1-5-9(6-2,7-3)8-4/h5-8H2,1-4H3/q+1
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 1.58E+5n/an/an/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of MPP+ uptake in Xenopus laevis oocytes

J Pharmacol Exp Ther 292: 1146-52 (2000)


BindingDB Entry DOI: 10.7270/Q2XS5WPJ
More data for this
Ligand-Target Pair
Solute carrier family 22 member 1


(Homo sapiens (Human))		BDBM50149890
PNG
(CHEMBL9324 | tetraethylammonium)
Show SMILES CC[N+](CC)(CC)CC
Show InChI InChI=1S/C8H20N/c1-5-9(6-2,7-3)8-4/h5-8H2,1-4H3/q+1
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 1.61E+5n/an/an/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of TEA uptake in OCT1-expressing HeLa cells

J Pharmacol Exp Ther 286: 354-61 (1998)


BindingDB Entry DOI: 10.7270/Q28P63DW
More data for this
Ligand-Target Pair
Solute carrier family 22 member 1


(Homo sapiens (Human))		BDBM50149890
PNG
(CHEMBL9324 | tetraethylammonium)
Show SMILES CC[N+](CC)(CC)CC
Show InChI InChI=1S/C8H20N/c1-5-9(6-2,7-3)8-4/h5-8H2,1-4H3/q+1
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 1.63E+5n/an/an/an/an/an/an/an/a



University of California San Francisco

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of MPP+ uptake in Xenopus laevis oocytes

Mol Pharmacol 51: 913-21 (1997)


Article DOI: 10.1124/mol.51.6.913
BindingDB Entry DOI: 10.7270/Q2154KWV
More data for this
Ligand-Target Pair
High affinity choline transporter 1


(Mus musculus)		BDBM50149890
PNG
(CHEMBL9324 | tetraethylammonium)
Show SMILES CC[N+](CC)(CC)CC
Show InChI InChI=1S/C8H20N/c1-5-9(6-2,7-3)8-4/h5-8H2,1-4H3/q+1
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 2.60E+5n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome

Bioorg Med Chem Lett 20: 4870-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.090
BindingDB Entry DOI: 10.7270/Q29C6XMQ
More data for this
Ligand-Target Pair
Solute carrier family 22 member 1


(RAT)		BDBM50149890
PNG
(CHEMBL9324 | tetraethylammonium)
Show SMILES CC[N+](CC)(CC)CC
Show InChI InChI=1S/C8H20N/c1-5-9(6-2,7-3)8-4/h5-8H2,1-4H3/q+1
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 2.86E+5n/an/an/an/an/an/an/an/a



The University of Texas M. D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of dTub uptake in Xenopus laevis oocytes

Biochem Pharmacol 60: 215-9 (2000)


BindingDB Entry DOI: 10.7270/Q2J38TN3
More data for this
Ligand-Target Pair
Solute carrier family 22 member 3


(Homo sapiens (Human))		BDBM50149890
PNG
(CHEMBL9324 | tetraethylammonium)
Show SMILES CC[N+](CC)(CC)CC
Show InChI InChI=1S/C8H20N/c1-5-9(6-2,7-3)8-4/h5-8H2,1-4H3/q+1
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 1.37E+6n/an/an/an/an/an/an/an/a



Medical College of Georgia

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of MPP+ uptake in OCT3-expressing HRPE cells

Am J Physiol Renal Physiol 279: 449-58 (2000)


Article DOI: 10.1152/ajprenal.2000.279.3.f449
BindingDB Entry DOI: 10.7270/Q2708482
More data for this
Ligand-Target Pair
Solute carrier family 22 member 1


(Mus musculus)		BDBM50149890
PNG
(CHEMBL9324 | tetraethylammonium)
Show SMILES CC[N+](CC)(CC)CC
Show InChI InChI=1S/C8H20N/c1-5-9(6-2,7-3)8-4/h5-8H2,1-4H3/q+1
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n/an/a 540n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of MPP+ uptake (MPP+: 1 uM) in Xenopus laevis oocytes

Biochem Biophys Res Commun 296: 644-50 (2002)


BindingDB Entry DOI: 10.7270/Q2P84D6R
More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Mus musculus)		BDBM50149890
PNG
(CHEMBL9324 | tetraethylammonium)
Show SMILES CC[N+](CC)(CC)CC
Show InChI InChI=1S/C8H20N/c1-5-9(6-2,7-3)8-4/h5-8H2,1-4H3/q+1
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n/an/a 3.50E+3n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of MPP+ uptake (MPP+: 1 uM) in Xenopus laevis oocytes

Biochem Biophys Res Commun 296: 644-50 (2002)


BindingDB Entry DOI: 10.7270/Q2P84D6R
More data for this
Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 1


(Homo sapiens (Human))		BDBM50149890
PNG
(CHEMBL9324 | tetraethylammonium)
Show SMILES CC[N+](CC)(CC)CC
Show InChI InChI=1S/C8H20N/c1-5-9(6-2,7-3)8-4/h5-8H2,1-4H3/q+1
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n/an/a 3.00E+4n/an/an/an/an/an/a



Dublin Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of Kv1.1 (unknown origin)

J Med Chem 60: 2245-2256 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01262
BindingDB Entry DOI: 10.7270/Q29K4DHG
More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Homo sapiens (Human))		BDBM50149890
PNG
(CHEMBL9324 | tetraethylammonium)
Show SMILES CC[N+](CC)(CC)CC
Show InChI InChI=1S/C8H20N/c1-5-9(6-2,7-3)8-4/h5-8H2,1-4H3/q+1
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n/an/a 1.56E+5n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of MPP+ uptake (MPP+: 1 uM) in Xenopus laevis oocytes

Pharm Res 19: 1244-7 (2002)


BindingDB Entry DOI: 10.7270/Q2T154ZH
More data for this
Ligand-Target Pair
Solute carrier family 22 member 4


(Rattus norvegicus)		BDBM50149890
PNG
(CHEMBL9324 | tetraethylammonium)
Show SMILES CC[N+](CC)(CC)CC
Show InChI InChI=1S/C8H20N/c1-5-9(6-2,7-3)8-4/h5-8H2,1-4H3/q+1
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n/an/a 1.00E+6n/an/an/an/an/an/a



Medical College of Georgia

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of TEA uptake in Octn1-HRPE cells

Biochim Biophys Acta 1466: 315-27 (2000)


Article DOI: 10.1016/s0005-2736(00)00189-9
BindingDB Entry DOI: 10.7270/Q2377CKS
More data for this
Ligand-Target Pair
Solute carrier family 22 member 3


(Homo sapiens (Human))		BDBM50149890
PNG
(CHEMBL9324 | tetraethylammonium)
Show SMILES CC[N+](CC)(CC)CC
Show InChI InChI=1S/C8H20N/c1-5-9(6-2,7-3)8-4/h5-8H2,1-4H3/q+1
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n/an/a 1.03E+7n/an/an/an/an/an/a



Universidade do Porto

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of MPP+ uptake (MPP+: 0.2 uM) in OCT3-expressing HEK293 cells

Naunyn Schmiedebergs Arch Pharmacol 363: 40-9 (2001)


BindingDB Entry DOI: 10.7270/Q2GQ702R
More data for this
Ligand-Target Pair